Run the Auto Play Repair Tool (Line 234) http://www.kellys-korner-xp.com/xp_tweaks.htm
The Autoplay feature may not start the correct Autorun command from a CD-ROM or a DVD-ROM
Check your settings here: Control Panel/Administrative Tools/Services/Shell Hardware Detection/Return this service to Automatic.
Enable CD AutoPlay for Pro or Home (Line 10) http://www.kellys-korner-xp.com/xp_tweaks.htm
If you are using TweakUI/My Computer/AutoPlay http://www.microsoft.com/windowsxp/pro/downloads/powertoys.asp
Many users have solved this issue by removing the AutoPlay Handlers. Details provided here:
More information here under AutoPlay Enable http://www.kellys-korner-xp.com/xp_a.htm#enable